Doxycycline is a broad spectrum antibiotic with a bacteriostatic or bacteriocidal action depending on the dose used. It has excellent absorption and tissue penetration, superior to most other tetracyclines. It is active against both Gram-negative and Gram-positive bacteria, rickettsiae, mycoplasmas, chlamydia, actinomyces and some protozoa.
Colistin is a bactericidal antibiotic active against Gram-negative bacteria (eg. E. coli, Salmonella, Pseudomonas). There is very low occurence of resistance. The absorption from the gastro-intestinal tract is poor, resulting in high concentrations in the intestines for treatment of bowel infections.
The association of both antibiotics shows excellent activity against systemic infections, as well as against gastro-intestinal infections. Therefore, DOXYCOL-50 is especially recommended for mass medication under circumstances that need a broad prophylactic or metaphylactic approach (eg. stress situations).
Treatment and prevention of:
Calves, lambs, pigs: respiratory infections (eg. bronchopneumonias, enzootic pneumonia, atrophic rhinitis, pasteurellosis, Haemophilus infections in pigs), gastro-intestinal infections (colibacillosis, salmonellosis), oedema disease in pigs, septicaemia.
Poultry: infections of the upper respiratory tract and air sacs (coryza, CRD, infectious sinusitis), E. coli infections, salmonellosis (typhose, paratyphose, pullorose), cholera, aspecific enteritis (blue-comb disease), chlamidiosis (psitacosis), speticaemias.
Do not use in animals with a previous history of hypersensitivity towards tetracyclines.
Do not use in ruminant calves.
DOSAGE AND MODE OF ADMINISTRATION
Calves, lambs, pigs: Treatment: 5 g powder per 20 kg b.w. per day for 3-5 days
Prevention: 2.5 g powder per 20 kg b.w per day
Poultry: Treatment: 100 g powder per 25-50 litres drinking water
Prevention: 100 g powder per 50-100 litres drinking water
Tetracyclines may seldom induce allergic reactions as well as gastro-intestinal disturbances (diarrhoea).
100g, 500g, 1kg, 5kg